In this study you'll visit the researchers of the Donders Centre for Cognition three times. At home, you'll fill in a questionnaire after the intake session. Additionally, you'll take the medication at home for 2 to 3 weeks.

1. The very first step involves a prescreening over the phone. During this phone appointment, we will go through the medical questionnaire that you had to complete before this appointment.
2. Afterward, you will be invited to an intake session at the Maria Montessori building on the Radboud University campus. During this session, we will administer questionnaires, measure your blood pressure and heart rate, and have you perform certain behavioral tasks. This session lasts approximately 3 hours.
3. After this session, you will complete several online questionnaires at home, taking about 1 hour.
4. During the initial testing session, you will return to our research center in the Maria Montessori building on the Radboud campus in Nijmegen. Here, you will fill out several questionnaires; your blood pressure, heart rate, and body temperature will be measured; and you will perform some computer tasks (lasting about three hours). Women will be offered a pregnancy test to ensure there is no pregnancy. At the end of this session, you will receive the medication pot to take home. Adequate breaks are scheduled, and you will receive a snack from us. In total, this session will take about 5 hours.
5. At home, you will take the escitalopram or placebo medication for 2 to 3 weeks. You will take one tablet per day. A member of the research team will contact you every 4 days to check if everything is going alright.
6. On the third and final testing day, you are welcome again at the Maria Montessori building on the Radboud campus in Nijmegen. We will again measure your blood pressure, heart rate, and body temperature. You will also fill out several questionnaires and perform computer tasks lasting about three hours. Adequate breaks are scheduled, and you will receive a snack from us. In total, this session will take about 5 hours.

You will receive escitalopram or a placebo every day for a maximum of 21 days. In previous studies, escitalopram has been given to healthy participants without them experiencing severe side effects. The most common side effects during clinical treatments with escitalopram include:
• drowsiness;
• difficulty sleeping;
• increased sweating;
• dry mouth;
• nausea;
• decreased appetite;
• nervousness/agitation;
• decreased libido.
All procedures you will undergo in the study are harmless. Some procedures may be perceived as unpleasant. In one of the computer tasks, an annoying sound will be played, which may be experienced as irritating.